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Clinical Pharmacology and Toxicology Staff

Chairman

Professor C.F.B Nhachi,
Professorial Chair of Clinical Pharmacology & Toxicology
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B.Sc. (Hons). Pharmacol. Aberdeen,; M.Sc. Med. Chem. Loughboough;
M.Sc.  Appl. Adv. Tox. Surrey;  Ph.D.  Clin. Pharmacol      & Tox.  London
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Senior Lecturer
Dr S Khoza
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B. Pharm (Hons); MSc Clin Pharmacol; MSc Clin Epi UZ; PhD (Texas)
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Senior Lecturer
Dr A Matimba
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B.Sc. (Hons). Biochemistry. UZ; M.Sc. Molecular Biology, University of Leuven Belgium; Ph.D. Human Genetics, University of Cape Town
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Lecturer
Ms T Mawoza
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B Pharm; MSc Pharmacology; SACORE PhD fellow
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Lecturer
Dr A C Reid
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MRCP (UK)
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Lecturer
Mr S Gavi
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MS Epid,  (Hons)B Pharm; HIV Pharmaceutical Care Specialist
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Office and Information Manager
Mrs M R Madyambudzi,
B.ED (EPPS); Dip Industrial Relations
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Office and Information Manager:
Ms B Mabhugu,
BA Med Studies, Dip Invest Journalism; NC Sec Studies
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Chief Technician
Mr W Murambiwa,:
AIST (UK)
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Senior Technician
Mr S Julius
BSc Agr Mgt, ND App  Chem Tech
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Nursing Sister
Sister N Chifamba,
RGN, Midwife, DNA
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">Technical Assistant
Mr B Chakururama

Dr A C Reid

Lecturer

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MRCP (UK)

Publications (in the last 3 years)

(a)    Kityo C, Walker AS, Dickinson L, Lutwama F, Kayiwa J, Ssali F, Nalumenya R, Tumukunde D, Munderi P, Reid A, Gilks CF, Gibb DM, Khoo S; DART Trial Team. Pharmacokinetics of lopinavir-ritonavir with and without nonnucleoside reverse transcriptase inhibitors in Ugandan HIV-infected adults. Antimicrobial Agents & Chemotherapy 2010 Jul; 54(7):2965-73. Epub 2010 Apr 26

(b)   Walker AS, Ford D, Gilks C, Munderi P, Ssali F, Reid A, Katabira E, Grosskurth H, Mugyenyi P, Hakim J, Darbyshire JH, Gibb DM, Babiker AG. Daily cotrimoxazole prophylaxis in severely immunosuppressed adults in Africa started on combination antiretroviral therapy. Lancet 2010 Apr 10; 375(9722):1278-86. Epub 2010 Mar 27

(c)    Munderi P, Walker AS, Kityo C, Babiker AG, Ssali F, Reid A, Darbyshire JH, Grosskurth H, P Mugyenyi, Gibb DM, Gilks CF on behalf of the DART/NORA trial teams. Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48 week randomised comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 counts. HIV Medicine 2010 May; 11(5):334-44. Epub 2010 Feb 3

Dr A Matimba

Senior Lecturer

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B.Sc. (Hons). Biochemistry. UZ; M.Sc. Molecular Biology, University of Leuven Belgium; Ph.D. Human Genetics, University of Cape Town

                       

Publications (in the last 3 years)

(a)    Masimirembwa,C., Matimba,A.: Pharmacogenomics in Africa: Diversity as an  opportunity for personalized healthcare in Genomics Applications for the Developing World. Springer; 2012

(b)   Fridley,B., Batzler,A., Li,L., Li,F., Matimba,A.,  Jenkins,G., Ji,Y., Wang,L.,

Weinshilboum,R. Gene set analysis of purine and pyrimidine antimetabolites

cancer therapies. Pharmacogenet Genomics.2011 Nov;21(11):701-12.

(c)    Li,F., Fridley,BL., Matimba,A., Kalari,KR., Pelleymounter,L., Moon,I., Ji,Y., Jenkins,GD., Batzler,A., Wang,L., Weinshilboum,RM.: Ecto-5’-Nucleotidase (NT5E) and Thiopurine Cellular Circulation: Association with Cytotoxicity. Drug Metabolism and Disposition 2010; 38(12):2329-38.

Dr S Khoza

Senior Lecturer

Dr S Khoza

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B. Pharm (Hons); MSc Clin Pharmacol; MSc Clin Epi UZ; PhD (Texas)

Publications(in the last 3 years)

(a)     Gavaza P, Rascati K, Oladapo AO, Khoza S. The state of health economics evaluation in South Africa: A systematic review. Pharmacoeconomics 2012; 30(10):925-940.

(b)   Mudzviti T, Maponga CC, Khoza S, Ma Q, Morse GD. The impact of herbal drug use on adverse drug reaction profiles of patients on antiretroviral therapy in Zimbabwe. AIDS Research and Treatment.  2012;2012:434171.

(c)    Khoza S, Barner JC, Bohman TM, Rascati K, Lawson K, Wilson JP. Use of antidepressants and the risk of diabetes mellitus. Eur J Clin Pharmacol. 2012; 68(9):1295-1302

Research Interests

  • Diabetes
  • Adverse Drug Reactions
  • Counterfeit Medicine

Mr S Gavi

Lecturer

Mr S Gavi

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MS Epid,  (Hons)B Pharm; HIV Pharmaceutical Care Specialist

Publications (in the last 3 years)

                  

(a)    Paula Maisiri-Dube, Samuel Gavi, Tinashe Mudzviti, C. C. Maponga.  Impact of herbal remedies on adherence to antiretroviral drugs in Zimbabwe. STATUS: Abstract accepted for presentation at the IAPAC Conference, Miami, USA.  June 2012

(b)   Samuel Gavi; Tinashe Mudzviti; Farzia Sayidine; Qing Ma; Kathleen Tooley; Robin Difrancesco; Russell W Bessette; Charles C Maponga; Gene D Morse.  Establishing an International Network for Using Health Information Technology in HIV/TB Medication Management Research.  Poster presentation at the Association of Medical Informatics (AIMA) Conference.  San Francisco, California, USA. March 2011

(c)    Samuel Gavi, Faziya Sayidine, Maponga C C, Felton C, Pulkit Bhuptani, Morse G D, Difrancesco R, Tooley K M.  (2011)  Use of Electronic Health Information Technology in HIV/AIDS Research and practice. Centre ofExcellence in Biomedical Informatics and Bioinformatics, University at Buffalo.www.slideshare.net/amal_cubs/​ehit101-introductory-module

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