Prof. Christopher James Chetsanga
Phone: +263 772 138 619
Research Interests: Microbial ecology, nutrition composition of indigenous fruits, drug-drug interaction,
DNA damage and repair/Carcinogenesis.
Professor Chetsanga joined the Biochemistry Department in 1983 as a Senior Lecturer. Previously, he worked at the University of Michigan as a Full Professor of Biochemistry and Molecular Biology. He is interested in research focused on chemical carcinogenesis. This involves an analysis of both DNA damage caused by chemical carcinogens and enzymology of the damage repair. Professor Chetsanga has retired from active research activities.
List of Selected Publication
- Chetsanga C.J; Poccia D L; Hill R J; and Doly P; (1970). Stage-related transcription in sea urchin embryos and their chromatins. Cold Spring Harbour Symp. Quant, Biol. 35:629-635.
- Chetsanga C J: Boyd V; Peterson L; and Rushlow K; (1975). Single stranded regions in DNA of old mice. Nature 253:130.
- Chetsanga C J; Novetsky J; and Dimino M J; (1976c). Properties of rat liver mitochondrial RNA Polymerase. Molecular and Cellular Biochemistry 13:147-156.
- Chetsanga C J; and Lindahl T; (1979). Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from E.coli. Nucleic Acid Research 6:3673-3684.
- Chetsanga C J; and Frenette G P; (1983). Excision of aflatoxin B1-imidazole ring opened guanine from DNA by formamidopyrimidine- DNA glycosylase. Carcinogenesis 4:997-1000.
- Chetsanga C J; and Grigorian C; (1983). A dose-response study on opening of the imidazole ring of adenine in DNA by ionising radiation. International J.of Radiation Biol. 44:321-331.
- Chetsanga C J and Mavunga I; (1986). Mechanisms of Chemical Reclosure of Opened Imidazole Ring of Guanine. Chemical-Biological Interactions 58:117-121.
- Chetsanga C J; Pettersson B; Pettersson U; Gyllensten U; (1991). Detection of human papilloma virus DNA by the polymerase chain reaction. Intl. J. Gynecological Cancer, 1:209-213.
- Chetsanga C J; Malmstrom P A; Gyllensten U; Moreno-Lopez J; Dintzer Z; and Pettersson U; (1992). Low incidence of human papilloma virus type 16 DNA in bladder tumour detected by the polymerase chain reaction. Cancer 69: 1208-1211.
- Chetsanga C J, Nanotechnology in health sciences. Emerging Technologies: Nanotechnology for Equitable Development. Conference Organised by the University of California – Santa Barbara and Woodrow Wilson International Centre for Scholars. Washington DC, USA. November 4-6 2009.