Department of Pharmacy

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Name :Dr C.C. Maponga

Position: Director

 

B. Pharm (Zim) – 1982, MPS (Ohio Northern University), PharmD. (State of New York at Buffalo) – 1988, MHPE (University of Illinois at Chicago) - 1997

He joined the University in 1988 in Clinical Pharmacy and Pharmacy Practice section as a lecturer. He became the Chairman by then the Department of Pharmacy in 1991 – 1994. In 1995 he became the Director of Zimbabwe National Drug and Toxicology Information Service (DaTIS) which is under the School of Pharmacy. In 2002 he became the chairman of the department again up to 2005. In 2002 he became the Senior Lecturer in Clinical Pharmacy. In the year 2010 he became the Director of the School up to present. His research interest is focused on HIV Clinical Pharmacology, Curriculum Development and Traditional Medicines. Currently he is also the Chairperson of the Traditional Medical Practitioners’ Council, Member of the Medicines Control Authority of Zimbabwe, Member of the Pharmacists Council of Zimbabwe, Member of the Traditional Medicines Ethics Research committee of the Medical Research Council, Founder and Chairperson of the Chronic Therapy Association of Zimbabwe and Patron of Research Pharmacists in Zimbabwe. He has published the following papers:-

 

  1. Morse GD, Maartens G, Maponga CC, Ma Q. Global HIV/AIDS Clinical and Translational Pharmacology. AIDS Research and Treatment 2012.
  1. 2.Mudzviti T, Maponga CC, Khoza S, Ma Q, and Morse GD. The impact of herbal drug use on adverse drug reaction profiles of patients on antiretroviral therapy in Zimbabwe. AIDS Research and Treatment - Research Article 434171.
  2. 3.Monera TG, Maponga CC. Prevalence and Patterns of Moringa oleifera Use among HIV Positive Patients in Zimbabwe: A Cross-Sectional Survey. Journal of Public Health in Africa [paper no. 42].
  3. 4.Mudzviti T, Sibanda M, Gavi S, Maponga CC, Morse GD. Implementing a pharmacovigilance program to evaluate cutaneous adverse drug reactions in an antiretroviral therapy program. Journal of Infection in Developing Countries - ID#1908 - ID#1908 - ID#1908 (acceptance letter)
    1. a.http://www.phishare.org/files/1891_Zimbabwe_ARV_Assessment_Format_Final.pdf
    1. Fehintola FA, Akinyinka OO, Adewole IF, Maponga CC, Ma Q, Morse GD. Drug Interactions in the Treatment and Chemoprophylaxis of Malaria in HIV infected individuals in sub Saharan Africa. Current Drug Metabolism 2011; 12: 51-56. PMID: 21222586 [PubMed - as supplied by publisher].
    2. Bepe N, Madanhi N, Mudzviti T, Gavi S, Morse G, Maponga CC. The impact of herbal remedies on adverse effects and quality of life in HIV-infected individuals on antiretroviral therapy. Journal of Infection in Developing Countries 2011; 5(1): 48-53. PMID: 21330740 [PubMed - indexed for MEDLINE]
    3. Lockman S., Hughes M.D., McIntyre et.al., C.C. Maponga (team member acknowledged) Antiretroviral Therapies in Women after Single Dose Nevirapine Exposure, National Institute of Health Public Access, N Engl J Med 2010 October 14; 363 (16): 1499 – 1509. DOI: 10. 1056/NEJMoa0906626
    4. Gwaza L, Wolfe AR, Benet LZ, Guglielmo BJ, Chagwedera TE, Maponga CC, Masimirembwa CM. In vitro inhibitory effects of Hypoxis obtusa and Dicoma anomala on cyp450 enzymes and p-glycoprotein. African Journal of Pharmacy and Pharmacology 2009; 3 (11): 539-546.
    5. Gavaza P, Simoyi T, Makunike B, Maponga CC. The prices people pay for medicines in Zimbabwe. Central African Journal of Medicine 2009 Jan-Apr; 55(1-4):14-9. PMID: 21977842 [PubMed - indexed for MEDLINE]
    6. Govo M, Gavaza P, Maponga CC, Mukosera KT. Community Pharmacy Users’ characteristics, reasons for visit to the pharmacy and their perceptions of the role of community pharmacists in Harare. East and Central African Journal of Pharmaceutical Sciences 2008; 11: 25 - 30. http://ajol.info/index.php/ecajps/article/view/44763
    7. Monera TG, Wolfe A, Maponga CC, Benet LZ, Guglielmo J. Moringa  oleifera leaf extracts inhibit 6b-hydroxylation of testosterone by CYP3A4. Journal of Infection in Developing Countries 2008; 2 (5): 379 383. PMID: 19745507

 

  1. Hur D, DiFrancesco R, Hochreiter J, Ma Q, Slish J, Maponga CC, Morse GD. Review of HIV-1 protease inhibitor assay methods. Current Pharmaceutical Analysis 2007; 3: 180-185.
  2. Maponga CC, Ma Q, Slish JC, Morse GD. HIV Pharmacotherapy issues, challenges, and priorities in sub-Saharan African countries. Top HIV Med. 2007; 15: 104-110. PMID: 17598930
  3. Ball DE, Tagwireyi D, Maponga CC. Drug information in Zimbabwe: 1990-1999 Pharmaceutical World Science 2007; 29: 131-6. PMID: 17342443
  4. Tsabasvi E, Gavaza P, Maponga CC. Harare doctors support the need for training in basic business economics principles in medical school: a pilot study. Central African Journal of Medicine 2006; 52 (7/8): 87- 89. PMID: 20355677
  5. Matema S, Gavaza P, Maponga CC. Pilot study of the role of pharmacists in the
    use of veterinary pharmaceutical products in Harare and Chitungwiza,
    Zimbabwe. Eastern and Central African Journal of Pharmaceutical Science 2006; 8 (3): 50 -53.
  6. Kaisi T, Maponga CC, Gavaza P, and Pazvakavambwa IE. An Assessment of the Extent of Use of Off-License and Unlicensed Drugs on Children at Parirenyatwa Hospital in Harare, Zimbabwe. Eastern and Central African Journal of Pharmaceutical Science 2006; 9: 3 -7.
  7. Mansfield D., Muhammad A.C., Ayala J.A, Berg C., Diskul D., Hutrado-Pascal F., Kalinin M., Mannan H., Maponga CC, Uribe V.E.R., Wanpeng Z. Alternative Development: A Global Thematic Evaluation Final Sythesis Report, United Nations Office on Drugs and Crime 2005. p 1-33
  8. Maponga CC, Report of the Desk Study Conducted in Preparation for Discussion on Harmonisation of National Reporting Requirements for ART Medicines Supply Management, IDA Solutions, Desk study for AIDS Medicines and Diagnostic Services, October 2005, p1-41.
  9. Gara CP, Pazvakavambwa I, Maponga CC, Gavaza P. An investigation of the factors influencing the choice of infant feeding methods among urban Zimbabwean women in the context of HIV transmission. Central African Journal of Medicine 2005; 50: 1-4. PMID: 16892856
  10. Sibanda N, Gavaza P, Maponga CC, Mugore L. Pharmaceutical manufacturer's compliance with drug advertisement regulations in Zimbabwe. American Journal of Health-System Pharmacy 2004; 61: 2678-81. PMID: 15646703
  11. Saruchera S, Gavaza P, Maponga CC, Tagwireyi D. Medication counseling in Zimbabwe. American Journal of Health-System Pharmacy, 2004 Aug 1, 62(15) 1554-5. PMID: 15372827
  12. Maponga C, Ondari C: The quality of antimalarials, a study in selected African countries. Geneva: World Health Organization WHO/EDM/PAR/2003. 4 2003.
  13. Shetty AK, Coovadia HM, Mirochnick MM, Maldonado YM, Mofenson LM, Eshleman SH, Fleming T, Emel L, George K, Katzenstein SH, Well J, Maponga CC, Mwatha A, Jones SA, Karim SSA, Bassett MT. Safety and trough concentrations of nevirapine prophylaxis give daily, twice weekly, or weekly in breast-feeding infants from birth to 6 months. Journal of Acquired Immune Deficiency Syndrome 2003; 34:482-490. PMID: 14657758
  14. Noguera M, Alt D, Hirschhorn L, Maponga C, Osewe P, Sam-Abbenyi A. Zimbabwe: Antiretroviral Therapy Program – Issues and Opportunities for Initiation and Expansion. Arlington, VA.: DELIVER/John Snow, Inc., 2003, for USAID; p1 - 127.
  1. Tsoto C, Maponga CC, Gwata S.       Developing a computer database for registering and monitoring patients on chronic drug therapy to determine drug consumption: a pilot study. Central African Journal of Medicine 2002; 47: 191-6. PMID: 12808765
  2. Maponga CC, Tetteh R. Report of a rapid needs assessment and framework for implementation of Ghana’s Drug Information System. Ghana National Drug Program. Accra, Ghana 2000.
  3. Maponga CC. The Drug Regulatory System in Zimbabwe. Country Report: Multi-Country Study on Effective Drug Regulation. World Health Organisation 1998 Essential Drugs Programme p1-149.
  4. Were WM, Nathoo KJ, Bannerman CH, Siziya S, Tarumbwa A, Chigonde S, Maponga CC. Once versus thrice daily intramuscular gentamicin in children with systemic infections. Central African Journal of Medicine 1997; 43: 63-67.
  5. Maponga CC, Nazerali H, Mugwindiri C, Wingwiri M. Cost implications of TB/HIV co-epidemic and drug therapy of TB in Zimbabwe. Journal of Social and Adminstrative Pharmacy 1996; 13: 20-29.
  6. Chisadza E, Maponga CC, Nazerali H. User fees and drug pricing policies: a study at Harare Central Hospital, Zimbabwe. Health Policy and Planning 1995; 10: 319-326. PMID: 10151850
  7. Maponga CC, Feresu AS. A community-based clinical pharmacy teaching, research and service program in Zimbabwe. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 1995; 15: 614-620. PMID: 8570434
  8. Kasilo O.M.J., Maponga CC., Manpower survey of Zimbabwe’s Pharmacy Profession, Manpower Monitor 1995; 1-3.
  9. Maponga CC. Journal of Applied Science in Southern Africa 1995; 1: 113- 114. Book Review of Parasitic Diseases by Bozdech   and Mason. University of Zimbabwe Publications 1993
  10. Maponga C, Barlow JC, Schentag JJ. Lack of effect of piroxicam on theophylline clearance in healthy volunteers. Drug Intelligence and Clinical Pharmacy: Annals of Pharmacotherapy 1990; 124: 123-6. PMID: 2309506

 

Professor T.E Chagwedera

 BSc. USL, MSc MGill, PhD Laval

 He is a Professor in the Pharmaceutical Chemistry Section. He was the Chairman of the then department of Pharmacy in the year 1987 – 1990. His research interest is in Pharmacognosy. He is a Member of the Medicines Control Authority of Zimbabwe. He has published more than 100 papers in referred international journals

 

 

Professor L.S. Chagonda

 

BSc Hons (Chem) – 1978, MSc (Medicinal Chemistry and Drug Metabolism) UK – 1979, PhD (Medicinal Chemistry) UK – 1982, MSc (Pharmacy) UK - 1986

He is an Associate Professor in the Pharmaceutical Chemistry Section. He was the first director of the school in 2006 – 2010. His research interest is in Medicinal Chemistry and Essential Oils. He is a member of various Pharmaceutical Societies. He had published the following papers:-

 

  1. 1.MUNODAWAFA T., CHAGONDA L.S., VIOL I., MUCHUWETI M., MOYO R.S., (2010). Total Phenolic Content and Antioxidant Activity of Some Zimbabwean Traditional Medicinal Plants. Recent Progress in Medicinal Plants Vol. 29 Drug Plants III. p.364 – 373.
  2. 2.CHAGONDA L.S., MUNODAWAFA T., VIOL D.I., MOYO S.R, (2009) Phytochemical, biological and antimicrobial evaluation of the most commonly used and threatened traditional medicinal plants in 5 select districts of Zimbabwe, Walter Sisulu University Research Conference 2009 August 25 – 27 Proceedings
  3. 3.CHAGONDA L.S., (2007) The potential of Traditional Medicines for the Treatment of HIV/AIDS and Opportunistic Infections (OIs) in Zimbabwe. SANBio Conference Proceedings of the first NEPAD/SANBio workshop on scientific validation of traditional medicine for affordable treatments of HIV/AIDS and opportunistic infections 15 – 16 March 2007, Lusaka, Zambia. Pp 59 – 60.

4.DZINGIRAI B., MUCHUWETI M., MURENJE T., CHIDEWE C., BENHURA M.A.N., CHAGONDA L.S., (2007) Phenolic content and phospholipids peroxidation inhibition by methanolic extracts of two medicinal: Elionurus muticus and Hypoxis hemerocallidea. African Journal of Biochemistry Research Vol.1 (7). Pp 137 – 141.

5.MUCHUWETI M., NYAMUKONDA L., CHAGONDA L.S., NDLALA A.R., MAPURE C., and KASIYAMHURU A., (2006). Total phenolic content and Antioxidant activity in selected medicinal plants of Zimbabwe, J. Food Science and Technology, 41 (1), p.33-38.

6.CHAGONDA L.S. and CHACHAT JC, (2005). The essential oil of the fruit of Garcinia huillensis Welw. ex Oliv. from Zimbabwe, Flav. Fragr. J, 20, p. 313-315.

7.CHAGONDA L.S. and CHALCHAT JC, (2005). The essential oil of wild and cultivated of Hoslundia opposita from Zimbabwe, Flav. Fragr. J, 20, p. 193-195.

8.CHAGONDA L.S. and CHALCHAT JC, (2005). The composition of the leaf essential oil of Satureja punctata (Benth) Briq. from Zimbabwe, Flav. Fragr J, 20, p. 316-317,

9.CHAGONDA, L.S. MAKANDA, C. AND CIIALCHAT, J-C.( 2000). The Essential Oils of cultivated Heterophyxis natalensis (Harv,) and cultivated Heteromorpha trifoliata (Wendl) Eckl and Zey from Zimbabwe. J. Essent. Oil Res. 12, 317 - 321.

10.CHAGONDA, L.S. MAKANDA, C. AND CHALCHAT, J-C.( 2000 ). The Essential Oils of Ocimum canum Sims (Basilic camphor) and Ocimum urticifolia Roth from Zimbabwe, Flav. Fragr J, 15, 23-26

11.CHAGONDA, L.S. MAKANDA, C. and CHALCHAT, J-C. (2000 ).The Essential Oils of wild and cultivated Lippia javanica (Spreng) and of Lippia oatessii (Rolfe) from Zimbabwe. J. Essent Oil Res 12, 1 - 6.

12.CHAGONDA, L.S. MAKANDA, C. and CHALCHAT, J-C. (2000). The Essential Oils of cultivated Cymbopogon winterianus ( Jowitt ) and of citratus ( Stapf. ) from Zimbabwe. J. Essent. Oil Res., 12, 478-480.

13.CHAGONDA, L.S. MAKANDA, C. and CHALCHAT, 3-C. (2000). The Essential Oils of wild and cultivated Cymbopogon validus (Stapf) Stapf ex Burtt Davy and Elionurus muticus (Spreng) Kuntze from Zimbabwe. Flav. Fragr J, 15, 100- 104.

14.CHAGONDA, L.S. MAKANDA, C. and CHALCHAT, 3-C. (1999) Essential Oils of Four Wild and semi-wild Plants from Zimbabwe Colospermum mopane, Helichrysurn splendidum (Thunb.). Less, Myrothamnus flabellifolia (Welw.) and Tagetes minuta L. J. Essent Oil Res 11, 573-578.

15.CHAGONDA, L.S. MAKANDA, C. and CHALCHAT, 3-C. (1999) The Essential Oil of Cultivated Artemisia afra (Jacq.) from Zimbabwe.. Flav. Fragr J 14 ,140-142.

 

Dr D. Tagwireyi – Senior Lecturer

 

B Pharm (Hons) (University of Zimbabwe), GradDipTox, MAppSci(Tox) (RMIT University), DPhil (Clinical Pharmacy /Toxicology) (University of Zimbabwe)

He is a Senior Lecturer in the Clinical Pharmacy Section. His research interest is in Applied Toxicology, Ethnopharmacology, Neurobehavioural pharmacology. He is the Director of the Drug and Toxicology Information Service (DaTIS) and he is a member of the various professional and academic societies including the Pharmaceutical Society of Zimbabwe, Zimbabwe Young Academy of Sciences (Founding President), Network of African Poisons Centres and Applied Toxicologists (NAPCAT – Founding Secretary), the European Association of Poison Centres and Clinical Toxicologists (EAPCCT), NAPRECA-Zimbabwe .

 

SELECTED PUBLICATIONS

1.Gadaga LL, Tagwireyi D, Dzangare J, Nhachi CFB (2011). Acute Oral Toxicity and Neurobehavioural Toxicological Effects of a Hydroethanolic Extract of Boophone disticha in Rats. Human and Experimental Toxicology. 30 :972 – 980

2.Tagwireyi D, Ball DE, Nhachi CFB (2011). Snakebite Admissions in: Pattern, Clinical Presentation and Management. The Central African Journal of Medicine 57 (5/8): 17 – 22.

5.Tagwireyi D, Ball DE, Nhachi CFB (2006). Toxicoepidemiology in Zimbabwe: Pesticide Poisoning Admissions to Major Hospitals. Clinical Toxicology 44 (1): 59 - 66.

6.Tagwireyi D, Ball DE, Nhachi CFB (2006). Toxicoepidemiology in Zimbabwe: Admissions Resulting from Exposure to Paraffin (Kerosene). Clinical Toxicology 44 (2): 103 - 107.

7.Tagwireyi D, Ball DE, Nhachi CFB (2006). Differences and Similarities in Poisoning Admissions Between Urban and Rural Health Centres in Zimbabwe. Clinical Toxicology 44 (3): 233 - 242.

9.Tagwireyi D and Ball DE (2002). “Muti” poisoning in Zimbabwe. Tropical Doctor 32: 41-42.

10.Tagwireyi D, Ball DE, Nhachi CFB (2002). Poisoning in Zimbabwe: A survey of eight major referral hospitals. Journal of Applied Toxicology 22 (2): 99-105.

11.Ball DE, Tagwireyi D, Nhachi CFB (2002). Chloroquine Poisoning in Zimbabwe: a Toxicoepidemiological Study. Journal of Applied Toxicology 22 (5): 311-315.

12.Tagwireyi D, Ball DE, Nhachi CFB (2002). Traditional Medicine Poisoning in Zimbabwe: Clinical Presentation and Management in Adults. Human & Experimental Toxicology 21 (11): 579-586.

14.Tagwireyi D, Ball DE, Nhachi CFB (2001). Routine prophylactic antibiotic use in the management of snakebite. BioMed Central - Clinical Pharmacology 4:1 [cited 2 November 2001]. Available from: URL: http://www.biomedcentral.com/1472-6904/1/4/.

15.Tagwireyi D, Ball DE, Loga PJ, Moyo S (2000). Cantharidin poisoning due to “Blister Beetle” ingestion. Toxicon 38: 1865-1869.

Ball D, Norris P, Enlund H, Tagwireyi D, Awad A (2007). Diversity Amongst International Pharmacy Students. Pharmacy Education 7 (4): 379 - 386.

Ball DE, Tagwireyi D, Maponga CC, Morton TA (2007). Drug Information in Zimbabwe: 1990 - 1999. Pharmacy World & Science 29 (3): 131 - 136.

Saruchera S, Maponga CC, Gavaza P, Tagwireyi D (2004). Medication Counseling in Zimbabwe. American Journal of Health System Pharmacy 61 (15): 1554 - 1555.

Tagwireyi D and Ball DE (2001). The management of Elephant’s Ear poisoning.       Human & Experimental Toxicology 20 (4): 189-192.

 

 

 

Dr A. Dube – Lecturer

 

B Pharm (Hons) (University of Zimbabwe), M. Pharm (South Africa) 2006, PhD (Pharmaceutical Sciences) Australia 2011

 

He is a lecturer in the Pharmaceutics section. His research interest is in Nanoparticle drug delivery system for infectious diseases and formulation of herbal materials. He is a member of the College Faculty Board and other Pharmaceutical societies. He has published the following papers:-

 

1.Dube A., Nicolazzo J.A., Larson I., Chitosan nanoparticles enhance the intestinal absorption of the green tea catechins (+) –catechin and (-) –epigallocatechin gallate, European Journal of Pharmaceutical Sciences, doi: 10.1016/j.ejps.2010.06.010

2.Dube A., Ng, K., Nicolazzo, J.A., Larson I., (2010) Effective use of reducing agents and nonoparticle encapsulation in stabilising catechins in alkaline solution, Food Chemisty, 122, 662-667.

3.Dube A., Nicolazzo J.A., Larson I. Measurement of pico-molar concentrations of (-) –epigallocatechin gallate using a novel HPLC method following oral administration to mice (submitted to the European Journal of Pharmaceutical and Biopharmaceutical Sciences).

4.Dube A., Manthata, L.N., Syce, J.A. (2007). The design the evaluation of placebo material for crude herbals: Artemisia afra herb as a model. Phytotherapy Research, 21, 448-451.

 

 

 Mr I. Mutingwende – Lecturer

BSc Hons (Zim), MSc (Biotechnology), MBA University of Zimbabwe

 

He is a lecturer in the Pharmaceutical Chemistry section and is currently doing a PhD. His research interest is in Pharmaceutical Biotechnology and Pharmacognosy. He is a member of the College Faculty Board and BMBSZ. He also sits on a number of external boards. He has published the following papers:-

 

1.K. Chitindingu, J.F. Chitindingu, Mudadi A.N. Benhura, A. Marume, I. Mutingwende, M. Bhebhe and Muchuweti. Antioxidant capacity of bioactive compounds extracted from selected wild and domesticated cereals of Zimbabwe. African Journal of Biochemistry Col. 6(5), pp 62-68. 15 March 2012.

2.A. Marume, K. Chitindingu, I. Mutingwende (2012). Inappropriate use of promethazine and promethazine containing syrups in children under the age of three years in Zimbabwe, Central African Journal of Medicine (accepted for publication).

3.B. Zhou, A. Marume, M. Bhebhe, I. Mutingwende (2012). An investigation of Factors Affecting Health Consumers’ Choice of medical intervention in Zimbabwe (in press).

4.Rose Hayeshi, Isaac Mutingwende, William Mavengere, Vimbai Masiyanise, Stanley Mukanganyama (2007). The inhibition of human glutathione-S-transferases by plant polyphenolic compounds ellagic acid and curcumin. Food and Chemical Toxicology 44(2):386-389

 

Mrs T.L. Muchemwa – Lecturer

B. Pharm (Zim) – 1982, MSc (Pharmaceutical Quality Control) Strathclyde University Scotland

 

She is a lecturer in the Pharmaceutical Chemistry section. Her research interest is in Pharmacognosy and Pharmaceutical Chemistry. She is a member of the College Faculty Board, member of Pharmaceutical Society of Zimbabwe, member of the Infection Control of Zimbabwe, member of the Association of University Teachers and an appointed High Court assessor for Drugs Control Council.

 

Mrs T.G. Monera – Penduka, Lecturer

 

B. Pharm Hons (Zim) – 2005, MPhil (Zim) – 2009, PG Dip Clin Trials (London) - 2011

Ms Monera-Penduka is a Permanent Full-time Lecturer in the Pharmacy Practice and Clinical Pharmacy section and a Pre-doctoral Fellow with the State University of New York at Buffalo. Her research interests include the impact of traditional medicine on antiretroviral therapy, homosexual and heterosexual HIV prevention (PEP, PrEP, MC, microbicides) and Pharmacy Education. She has experience in a wide variety of pre-clinical in vitro, and in vivo techniques for assessing drug interactions, bioanalytical assay development and validation as well as pharmacokinetic data analysis and interpretation. In addition she has experience in clinical trials, protocol development and project management. Mrs Monera-Penduka has published the following papers:-

1.      Dudzai D. Mureyi, Tsitsi G. Monera and Charles C. Maponga.Prevalance and patterns of prenatal use of traditional medicine among women at selected Harare clinics: a cross-sectional study. BMC Complement Altern Med 12 (1): 164 (2012) PMID 23016608

2.      Tsitsi G. Monera and Charles C. Maponga. Prevalence and patterns of Moringa oleifera use among HIV positive patients in Zimbabwe: a cross-sectional survey. Journal of Public Health in Africa Vol3, No 1 2012-10-24

3.      Tsitsi G. Monera. The role of the Pharmacists in Clinical trials. The Pharmaceutical Journal of Zimbabwe Vol. 2, Issue 2, September (2009).

4.      Tsitsi G. Monera, Alan R. Wolfe, Charles C. Maponga, Leslie Z. Benet and Joseph Guglielmo. Moringa oleifera leaf extract inhibit 6beta-hydroxylation of testosterone by CYP3A4. J Infect Dev Ctries 2(5): 379 – 83 (2008) PMID 19745507

 

Mr N. Mafirakureva – Lecturer

B. Pharm Hons (Zim) 2007, MSc Medical Pharmaceutical Sciences, University of Groningen (Netherlands) 2011

 

He is a temporary full time lecturer in the Clinical Pharmacy and Pharmacy Practice section. He is a Pharmaceutical scientist and Health Economics researcher. Nyasha has experience in Drug Disposition & Toxicology as applied to drug development (2009 – 2011), as well as in medicines regulatory affairs (2007 – 2009). He holds a Doctoral research fellowship position in Health Economics at the University of Groningen. His research interests include economic evaluation of healthcare interventions, safety of therapies and pharmacometrics (Pharmacokinetic – Pharmacodynamic modeling). Currently, he is working on the health economics and safety of blood & blood products in Sub-Saharan Africa.

 

Mr L. Gadaga – Lecturer

 

B. Pharm (Zim) 2007, MPhil (Pharmacology and Toxicology) University of Zimbabwe, (2012)

 

He is a temporary full time lecturer in the Clinical Pharmacy and Pharmacy Practice section. His research interest is in Neurobehavioural Pharmacology, Ethnopharmacology, Clinical Toxicology and Toxicogenomics, and Pharmacogenomics. He is also a member of the Zimbabwe Drug Toxicology Information Centre (DaTIS) and a member of Pharmaceutical Society of Zimbabwe. He has published the following papers:-

 

1.Gadaga LL, Tagwireyi D, Dzangare J, Nhachi CFB (2011). Acute Oral Toxicity and Neurobehavioural Toxicological Effects of a Hydroethanolic Extract of Boophone disticha in Rats. Human and Experimental Toxicology. 30 :972 – 980

2.Dube T, Tagwireyi D, Gadaga L (2009). An Investigation of Antidepressant-Like Activity of Boophane Disticha in a Mouse Model. The Central African Journal of Medicine. Supp 55 (9/12), p 6

3.Chiswa O, Tagwireyi D, Gadaga L, Machingura I (2009). Acute Toxicity Study of the Hydroethanolic Extract of Boophane Disticha in a Mouse Model. The Central African Journal of Medicine. Supp 55 (9/12), p 5-6

4.Ganga T, Tagwireyi D, Gadaga L, Machingura I (2009). Sub-Acute Toxicity Study of a Hydroethanolic Extract of Boophane Disticha in a Rat Model. The Central African Journal of Medicine. Supp 55 (9/12), p 7

5.Zimbwa M, Tagwireyi D, Gadaga LL. An Investigative Study of the Memory Enhancement Properties of a Crude Hydroethanolic Extract of Boophane Disticha in a Mouse Model. The Central African Journal of Medicine. Supp 55 (9/12), p 9

6.Gwaze R, Tagwireyi D, Gadaga LL (2009). Evaluation of the Genotoxicity of a Crude Hydroethanolic Extract of Boophane Disticha Using the Ames Test. The Central African Journal of Medicine. Supp 55 (9/12), p 9

7.Magaranezano T, Tagwireyi D, Gadaga LL (2009). A Retrospective Study of Poisoning Cases Reported at Warren Park Polyclinic: 2005 – 2008. The Central African Journal of Medicine. Supp 55 (9/12), p 8.

8.Kanyemba JF, Gadaga LL, Tagwireyi D (2009). A Study to Assess the Quality of Standards and the Need for Drug and Toxicology Information Service. The Central African Journal of Medicine. Supp 55 (9/12), p 8-9

9.Gadaga LL, Mufukari N, Tagwireyi D (2009). Management of Paediatric Poisoning at a Referral Hospital in Zimbabwe. Clinical Toxicology 47 (7): p 745.

10.Gadaga LL, Mufukari N, Tagwireyi D (2008). Management of Paediatric Poisoning at a Referral Hospital. Clinical Toxicology 46 (7): p 619.

11.Tagwireyi D, Gadaga L, Ball DE, Nhachi CF (2005). A simple qualitative procedure for the detection of chloroquine in urine with potential for use in clinical analytical toxicology in developing countries: A preliminary report. Journal of Toxicology - Clinical Toxicology 43 (6): p 687-688.

12.Gadaga L.L., Tagwireyi D., Dzangare J., Nhachi C.F.B. Acute oral toxicity and neurobehavioural toxicology effects of hydroethanolic extract of Boophane disticha in rats. Human and Experiemental Toxicology in press

 

Mr T. Mudzviti – Lecturer

 

B. Pharm (Zim) 2006, MPhil (University of Zimbabwe) 2012

 

He is a temporary full time lecturer in the Clinical Pharmacy and Pharmacy Practice section and is currently doing his PhD. His research interest is in risk factors for pre-cancerous cervical lesions in HIV infected patients. He is also a member of the Zimbabwe Drug Toxicology Information Centre (DaTIS) and a member of the Pharmaceutical Society of Zimbabwe. He has published the following papers:-

 

1.Mudzviti T, Sibanda M, Gavi S, Maponga C.C., Morse G.D. Implementing a pharmacovigilance program to evaluate cutaneous adverse drug reactions in antiretroviral access program. Journal of Infection in Developing Countries (article 1908). In press

2.Mudzviti T., Maponga C.C., Khoza S, Ma Q, Morse G.D. The Impact of herbal drug use on adverse drug reactions profiles of patients on antiretroviral therapy in Zimbabwe. AIDS research and Treatment 2012 (article 434171)

3.Bepe N., Madanhi N., Mudzviti T., Gavi S., Maponga C.C., Morse G.D. The Impact of herbal remedies an adverse effects and quality of life in HIV-infected individuals on antiretroviral Management Research. New York HIV Research Centrers Consortium, 19 March 2010, New York, USA

4.Qing Ma, Adel Sulaimen, Cara Felton, Joshua Sawyer, Mudzviti T., et.al. Developinh an International Health Information Technology Network for HIV Medication Management Research. New York HIV Research Centrers Consortium, 19 March 2010, New York, USA

5.Mudzviti T., Khoza S. Thiazolidinediones in the management of type 2 diabetes: A systematic review and meta-analysis. Pharmaceutical Journal of Zimbabwe. March 2007, 1 (1). Pg 10

 

11.Mr E. Kudambo

 

 MSc Degree in Pharmaceutical Analysis and Quality Control of Drugs (University of London, Kings College, Chelsea), HND Chemisty, RGN (Law Hospital) Scotland.

 

He is a temporary full time lecturer in the Pharmaceutics section. His research interest is in chemical substances / drugs in the maize plant and analysis in pharmaceutical products.

 

 

In addition to the above the school is supported by the following staff members:-

 

Technical Section

Mr E. Bamu – Senior Chief Technician

Mr A. Tarumbwa – Senior Technician (Clinical Pharmacy section)

Mr J. Mutenure – Senior Technician (Pharmaceutics section)

Mr P. Hove – Senior Technician (Pharmaceutics section)

Mr B. Phiri – Senior Technician (Pharmaceutical Chemistry section)

Mr N. Chinzou – Senior Technician (Pharmaceutical Chemistry section)

Mr W. Pfukenyi – Senior Technician (Pharmaceutics section)

Mr E. Shito – Lab Assistant

Mr V. Kafura – Technical Assistant

 

Administration Section

Mrs S. Mudzvovera – Information and Office Manager

Ms R. M. Issa – Senior Secretary

Ms U. Hlongwane – Secretary (DaTIS)