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Dr A C Reid

Lecturer

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MRCP (UK)

Publications (in the last 3 years)

(a)    Kityo C, Walker AS, Dickinson L, Lutwama F, Kayiwa J, Ssali F, Nalumenya R, Tumukunde D, Munderi P, Reid A, Gilks CF, Gibb DM, Khoo S; DART Trial Team. Pharmacokinetics of lopinavir-ritonavir with and without nonnucleoside reverse transcriptase inhibitors in Ugandan HIV-infected adults. Antimicrobial Agents & Chemotherapy 2010 Jul; 54(7):2965-73. Epub 2010 Apr 26

(b)   Walker AS, Ford D, Gilks C, Munderi P, Ssali F, Reid A, Katabira E, Grosskurth H, Mugyenyi P, Hakim J, Darbyshire JH, Gibb DM, Babiker AG. Daily cotrimoxazole prophylaxis in severely immunosuppressed adults in Africa started on combination antiretroviral therapy. Lancet 2010 Apr 10; 375(9722):1278-86. Epub 2010 Mar 27

(c)    Munderi P, Walker AS, Kityo C, Babiker AG, Ssali F, Reid A, Darbyshire JH, Grosskurth H, P Mugyenyi, Gibb DM, Gilks CF on behalf of the DART/NORA trial teams. Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48 week randomised comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 counts. HIV Medicine 2010 May; 11(5):334-44. Epub 2010 Feb 3

Dr A Matimba

Senior Lecturer

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B.Sc. (Hons). Biochemistry. UZ; M.Sc. Molecular Biology, University of Leuven Belgium; Ph.D. Human Genetics, University of Cape Town

                       

Publications (in the last 3 years)

(a)    Masimirembwa,C., Matimba,A.: Pharmacogenomics in Africa: Diversity as an  opportunity for personalized healthcare in Genomics Applications for the Developing World. Springer; 2012

(b)   Fridley,B., Batzler,A., Li,L., Li,F., Matimba,A.,  Jenkins,G., Ji,Y., Wang,L.,

Weinshilboum,R. Gene set analysis of purine and pyrimidine antimetabolites

cancer therapies. Pharmacogenet Genomics.2011 Nov;21(11):701-12.

(c)    Li,F., Fridley,BL., Matimba,A., Kalari,KR., Pelleymounter,L., Moon,I., Ji,Y., Jenkins,GD., Batzler,A., Wang,L., Weinshilboum,RM.: Ecto-5’-Nucleotidase (NT5E) and Thiopurine Cellular Circulation: Association with Cytotoxicity. Drug Metabolism and Disposition 2010; 38(12):2329-38.

DR MILCAH DHORO

Dr Milcah Dhoro

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Qualifications: Doctor of Philosophy in Pharmacogenetics, University of Zimbabwe, 2015, Master of Philosophy Molecular Biology, University of Zimbabwe, 2010, Bachelor of Science Honors Biological Sciences, Midlands State University, 2004.

Bio: Dr Dhoro has more than 15 years of experience in the field of molecular biology in particular human genetics. Her research interests focus on understanding the effects of patient genetic variability with respect to disease susceptability and response to medicines, the discovery of safer and effective medicines and technological advancements in diagnostic tools that can contribute to improved disease detection, treatment and monitoring. After successful completion of her DPhil studies in 2015, she received a Fogarty/NIH Global Health Scholars fellowship to persue a postdoctoral fellowship. During this time she managed to receive various genetic testingtrainings and immunoassays at the University of Oxford, Nuffield Department of Medicine, United Kingdom; Frederick National Laboratory for Cancer Research, Maryland, USA and the Ragon Institute of Massachusetts General Hospital and Harvard in Boston, respectively. In August 2017, she received an award to attend a one month long International Summit in Human Genetics and Genomics which was hosted by the National Human Genome Research Institute (NHGRI) at the National Institutes of Health, USA. In 2019, she enrolled into a two-year Medical Genetics and Genomics Certificate program offered by the National Human Genome Research Institute at the NIH, USA and completed it in 2021. This has added to her research interests the understudied area of congenital birth defects in Zimbabwe. She has also participated in the SPARK-Global community- a partnership between universities and industries founded by Professor Daria Mochly-Rosen in 2006 at Stanford University in the USA. This global community provides the education and mentorship necessary to for translational research. Dr Dhoro is also a member of the Biobank and Cohort Network (BCNet) International Working Group- a network set-up to address challenges in biobanking and research including ethical, legal and social issues.

Research Interests: Pharmacogenetics, Human health and genomics, Biobanking and research, Molecular Diagnostics

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Phone Number: +263772391978

Publications: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/50197887/?sort=date&direction=ascending

Dr S Khoza

Senior Lecturer

Dr S Khoza

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B. Pharm (Hons); MSc Clin Pharmacol; MSc Clin Epi UZ; PhD (Texas)

Publications(in the last 3 years)

(a)     Gavaza P, Rascati K, Oladapo AO, Khoza S. The state of health economics evaluation in South Africa: A systematic review. Pharmacoeconomics 2012; 30(10):925-940.

(b)   Mudzviti T, Maponga CC, Khoza S, Ma Q, Morse GD. The impact of herbal drug use on adverse drug reaction profiles of patients on antiretroviral therapy in Zimbabwe. AIDS Research and Treatment.  2012;2012:434171.

(c)    Khoza S, Barner JC, Bohman TM, Rascati K, Lawson K, Wilson JP. Use of antidepressants and the risk of diabetes mellitus. Eur J Clin Pharmacol. 2012; 68(9):1295-1302

Research Interests

  • Diabetes
  • Adverse Drug Reactions
  • Counterfeit Medicine

Mr Louis Gadaga

Mr Louis Gadaga

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Qualifications: MPhil Medicine(Pharmacology and Toxicology2012) UZ , Bachelor of Pharmacy Honours Degree 2004 (UZ)

Biography

He is a lecturer in the Pharmaceutics and Clinical Pharmacy section.  He is the Director of the Drug and Toxicology Information Service and he is a member of various societies.  His research interest is in neuropharmacology, toxicity testing, natural products, nanotoxicology and nanomedicine, formulation and characterisation of novel oral delivery systems for the effective delivery of traditional medicines.  He has also supervised over 40 undergraduate honours research students.  He is currently embarking on his PhD.  He has over 10 publications.

Research Interests: Neuropharmacology, Toxicity testing, natural products, Nanotoxicology and nanomedicine formulation

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Phone Number: +263 772854552

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